Its not a matter of it being over drive or anything. Thats completely irrelevant.
The issue is that its a long gear. So your in it for a long time, thus the turbo is fully spooled and the motor is producing maximum hp for an extended period of time unlike the lower gears where its full power for a second maybe two, then shift.
The stresses are enormous! Also heat build up is a major issue as well. The exhaust housing and turbo manifold are likely red hot at this point. Certain ares of the head and also the center of your pistons are hundreds of degrees hotter than normal. All of it adds up to alot of stress simply from the longer than usual WOT with 100%+ load.
I would not agree that you "shouldnt" do it, but should be cautious. If something it going to break, its likely going to be in 4th or even more likely, 5th gear while WOT.