The frame itself bolts onto unadjustable locations but.....
-The old frame may be tweaked a bit and the car was aligned to compensate
-The new frame might be off compared to the rest of the car
-If you re-use your suspension arms the alignment will be disturbed upon assembly
-If the new frame comes with arms, who knows what the alignment was..
At least have it checked when you are done, some places will even do a check for free in hopes of selling you the alignment you are probably going to need anyways.