Start with the fuses in your engine bay, then move to the fuses in your car. (Easy that way, and It's likely something in the engine bay if your draining power that fast.)
Remember to check the fusable links too. (Huge fuses basicly.)
Once you find the fuse that when removed takes the load away, then go to the part that is fused, and check for signs of damage. Check the wires leading up to the part that you can see as well. (No need to buy a expensive part when you can see the harness wires have been crushed by a careless prior owner, or auto accident with crappy repairs to your wires before you owned the car.) A short is a short, in the wires or in the part, it's just a "leak" of power to ground. (However some would say the electrons are actually moving the other way around, but you get the point.)
Good luck, this takes time, so I hope you find your short on the very first fuse pull... (This can be easy if you see impact damage, or some old repairs, look for the parts that are in that area, and the wires in that area. Or if somone wired up a stereo or alarm, those are all suspect area's too.) Same goes for SAFC etc.